What it measures
- Total cholesterol
- HDL cholesterol
- LDL cholesterol
- Triglycerides
- Apolipoprotein B (ApoB)
- Lipoprotein(a)
Beyond a standard cholesterol test
A standard cholesterol test measures how much cholesterol is in your blood. This profile adds two markers that help refine your risk:
- ApoB counts the number of particles that carry “bad” cholesterol into artery walls. It can be raised even when LDL looks normal.
- Lipoprotein(a), or Lp(a), is a type of cholesterol particle that is largely inherited. A high level increases the risk of heart attack and stroke, and it’s recommended that adults have it measured at least once.
What happens next
Your report shows each result against its target range. If your results are raised, your GP can combine them with your blood pressure, age and other factors to work out your overall risk and discuss lifestyle changes or treatment.
Who it’s for
- A family history of heart disease or stroke
- High cholesterol, high blood pressure or diabetes
- Wanting more detail than a standard cholesterol test
How to prepare
- Drink plenty of water beforehand; it makes the sample quicker and easier to take.
- You don’t need to fast.
Cardiovascular Profile Blood Test: your questions
What is lipoprotein(a)?
Lp(a) is a cholesterol-carrying particle whose level is mostly set by your genes. A high level raises cardiovascular risk independently of your other cholesterol results, so it’s worth knowing once.
Do I need to fast?
No, fasting isn’t usually needed for a cholesterol profile.
Information on this page is general and doesn’t replace advice from your GP, midwife or consultant. If you feel unwell or are worried about symptoms, contact your GP, call NHS 111 or, in an emergency, 999.

