What it measures
- RPR
- Treponemal antibodies
Syphilis testing
Syphilis is a bacterial infection passed on through sexual contact. The first sign is often a painless sore that’s easy to miss, followed weeks later by a rash, but many people have no symptoms. Untreated, it can cause serious problems, so testing is important.
Most infections show on a blood test within 6 weeks of exposure. If your test is negative but you were exposed less than 12 weeks ago, repeat it at 12 weeks to be sure. Syphilis is easily treated with antibiotics through your GP or a sexual health clinic.
Who it’s for
- A new sexual partner or a partner with syphilis
- A painless sore or an unexplained rash
- A routine sexual health check
- Pregnancy planning
How to prepare
- Drink plenty of water beforehand; it makes the sample quicker and easier to take.
- You don’t need to fast.
Syphilis (RPR) Blood Test: your questions
How soon after exposure can I test for syphilis?
Most infections are detectable within 6 weeks. A repeat test 12 weeks after possible exposure confirms a negative result.
Information on this page is general and doesn’t replace advice from your GP, midwife or consultant. If you feel unwell or are worried about symptoms, contact your GP, call NHS 111 or, in an emergency, 999.